Spinal plasticity after PAS 1
نویسندگان
چکیده
1. Human Motor Control Section, National Institutes of Health, National Institute of Neurological Disorders & Stroke, 10 Center Drive Bldg 10 Room 5N240, Bethesda, Maryland 20892; 2. INSERM, U731, Paris, F-75651 France; 3. Université Pierre et Marie Curie-Paris6, UMR S731, Paris, F-75013 France 4. INSERM, U 825, Toulouse F-31059 France , Hôpital Purpan, Fédération de Neurologie, Toulouse F-31059 France
منابع مشابه
Spinal Excitability Changes after Transspinal and Transcortical Paired Associative Stimulation in Humans
Paired associative stimulation (PAS) produces enduring neuroplasticity based on Hebbian associative plasticity. This study established the changes in spinal motoneuronal excitability by pairing transcortical and transspinal stimulation. Transcortical stimulation was delivered after (transspinal-transcortical PAS) or before (transcortical-transspinal PAS) transspinal stimulation. Before and afte...
متن کاملPathway-specific plasticity in the human spinal cord.
The aim of the present study was to artificially induce plasticity in the human spinal cord and evaluate whether this plasticity is pathway specific. For this purpose, a technique called paired associative stimulation (PAS) was applied. Volleys evoked by transcranial magnetic stimulation over the primary motor cortex and peripheral nerve stimulation of the nervus tibialis in the popliteal fossa...
متن کاملChanges in spinal excitability after PAS.
Repetitive pairing of a peripheral stimulation with a magnetic transcortical stimulation (PAS) is widely used to induce plastic changes in the human motor cortex noninvasively. Based on the contrast between PAS-induced increase of corticospinal excitability and absence of PAS-induced increase of the spinal F wave size, it has been generally accepted that PAS-induced plasticity is cortical in or...
متن کاملFailure of spinal paired associative stimulation to induce neuroplasticity in the human corticospinal tract.
CONTEXT/OBJECTIVE Paired associative stimulation (PAS) involves paired-stimulation pulses at both the head (via transcranial magnetic stimulation) and the periphery (via peripheral nerve stimulation). The purpose of PAS, when applied to the spinal cord, is to induce neuroplasticity and upregulate the corticospinal tract leading to effector muscles. While limited research has suggested that it i...
متن کاملEarly visuomotor integration processes induce LTP/LTD-like plasticity in the human motor cortex.
To investigate whether visuomotor integration processes induce long-term potentiation (LTP) and depression (LTD)-like plasticity in the primary motor cortex (M1), we designed a new paired associative stimulation (PAS) protocol coupling left primary visual area (V1) activation achieved by hemifield visual evoked potentials (VEPs) and transcranial magnetic stimulation (TMS) over the left M1, at s...
متن کامل